Table 3. Estimated fixed effects assessing growth patterns and adult schizophrenia.
Unadjusted model | Adjusted model | |||||
---|---|---|---|---|---|---|
B | 95% Cl | P | B | 95% Cl | P | |
Early life (birth to 2½ years) | ||||||
Entire sample (n=7780) | ||||||
Mean height at birth, cm (intercept) | 52.59 | 52.51 to 52.66 | < 0.001 | 38.76 | 38.24 to 39.28 | < 0.001 |
Linear change in height, cm/year | 30.37 | 30.26 to 30.48 | < 0.001 | 30.37 | 30.25 to 30.48 | < 0.001 |
Quadratic change in height, cm/year2 | −6.69 | −6.74 to −6.64 | < 0.001 | −6.69 | −6.74 to −6.65 | < 0.001 |
Effect of SSD on birth length, cm | −0.09 | −0.77 to 0.58 | 0.784 | −0.20 | −0.64 to 0.24 | 0.375 |
Effect of SSD on linear growth, cm/year | 0.35 | −0.82 to 1.52 | 0.560 | 0.74 | −0.53 to 2.01 | 0.253 |
Effect of gender1 and SSD on growth, cm/year | −1.12 | −2.04 to −0.20 | 0.017 | −1.55 | −2.52 to −0.57 | 0.002 |
Females only (n=3802) | ||||||
Mean height at birth, cm (intercept) | 51.64 | 51.57 to 51.72 | < 0.001 | 38.51 | 37.79 to 39.23 | < 0.001 |
Linear change in height, cm/year | 29.54 | 29.40 to 29.68 | < 0.001 | 29.54 | 29.39 to 29.68 | < 0.001 |
Quadratic change in height, cm/year2 | −6.37 | −6.44 to −6.30 | < 0.001 | −6.37 | −6.44 to −6.31 | < 0.001 |
Effect of SSD on birth length, cm | −0.02 | −0.87 to 0.83 | 0.968 | −0.02 | −0.57 to 0.52 | 0.936 |
Effect of SSD on growth, cm/year | −1.03 | −1.73 to −0.33 | 0.004 | −1.26 | −2.00 to −0.53 | 0.001 |
Males only (n=3978) | ||||||
Mean height at birth, cm (intercept) | 52.46 | 52.39 to 52.54 | < 0.001 | 38.42 | 37.66 to 39.18 | < 0.001 |
Linear change in height, cm/year | 30.94 | 30.79 to 31.09 | < 0.001 | 30.95 | 30.79 to 31.10 | < 0.001 |
Quadratic change in height, cm/year2 | −6.97 | −7.04 to −6.91 | < 0.001 | −6.98 | −7.05 to −6.91 | < 0.001 |
Effect of SSD on birth length, cm | −0.03 | −0.70 to 0.64 | 0.921 | −0.16 | −0.59 to 0.28 | 0.480 |
Effect of SSD on growth, cm/year | 0.06 | −0.52 to 0.64 | 0.836 | 0.26 | −0.37 to 0.89 | 0.420 |
Later childhood (2½ to 9 years) | ||||||
Entire sample (n=7353) | ||||||
Mean height at age 2½ years, cm (intercept) | 91.00 | 90.87 to 91.13 | < 0.001 | 88.36 | 86.91 to 89.81 | < 0.001 |
Linear change in height, cm/year | 7.94 | 7.89 to 7.99 | < 0.001 | 7.94 | 7.89 to 7.99 | < 0.001 |
Quadratic change in height, cm/year2 | −0.22 | −0.23 to −0.22 | < 0.001 | −0.22 | −0.23 to −0.22 | < 0.001 |
Effect of SSD on height at age 2½ years, cm | 0.53 | −0.73 to 1.80 | 0.408 | 0.17 | −1.11 to 1.46 | 0.790 |
Effect of SSD on linear growth, cm/year | −0.08 | −0.62 to 0.46 | 0.769 | −0.04 | −0.63 to 0.55 | 0.896 |
Effect of gender and SSD on growth, cm/year1 | −0.16 | −0.61 to 0.29 | 0.478 | −0.21 | −0.70 to 0.27 | 0.389 |
SSD, schizophrenia-spectrum disorders: presence of SSD=1, absence of SSD=0.
Gender is categorised as female=1, male=0.