Table 1.
Summary of cases examined
| ACSR Number-Lab ID | HAD | Degree of Neuropathology1 | Other Primary Pathology2 | HAART3 |
|---|---|---|---|---|
| 3007238-NV | None | none | yes | |
| 3007235-KA | None | 1 | yes | |
| 3007241-FL | None | 1 | yes | |
| 3007239-YZ | None | 1 | yes | |
| 3007240-OK | None | 1 | yes | |
| 3007243-DE | None | 1 | yes | |
| 3007234-AZ | None | 3 | CVD | yes |
| 3007242-BW | Progressive | 2 | Meningeal Lymphoma | yes |
| 3007233-DY | Acute | 1 | MAC | yes |
| 3007244-GA | Progressive | 5 | Pulmonary Edema | yes |
| 3006990-CX | Progressive | 5 | no | |
The Degree of Neuropathology is estimated on a scale of 1 to 5, with 1 being slight edema and/or vacuolization or other similar minimal tissue damage and 5 being profound macrophage infiltration or other severe abnormalities. In the CVD patient, the primary neuropathology observed was atherosclerosis while in the lymphoma patient the primary neuropathology was leptomeningeal lymphoma.
All patients eventually died with multiple pathologies common to end-stage AIDS; noted in this column are the primary non-neurological causes of death of the patients, as shown in table 2, detectable HIV in most brain tissues.
HAART therapy was frequently stopped in the weeks or days prior to death.