Table 2. Biomarker Analysis of Nuclear and Cytoplasmic Ep-ICD Expression in Epithelial Cancers.
Ep-ICD Nuclear IHC Scores | AUC | Sensitivity (%) | Specificity (%) | PPV (%) | NPV (%) | Asymptotic Sig. |
Prostate Cancer vs. Normal | 0.867 | 82 | 78 | 95 | 44 | 0.001 |
Breast Cancer vs. Normal | 0.905 | 82 | 100 | 100 | 78 | 0.000 |
HNSCC vs. Normal | 0.822 | 65 | 95 | 97 | 49 | 0.000 |
ESCC vs. Normal | 0.630 | 37 | 90 | 90 | 38 | 0.001 |