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. 2010 Nov 30;5(11):e14152. doi: 10.1371/journal.pone.0014152

Table 1. Top phosphopeptides identified by peak intensities.

Gene Peptide T-test: 2 cGy:C T-test: 50 cGy:C 2 cGy/C 50 cGy/C Site PotentialKinase
SASH1 R.TCS*FGGFDLTNR.S 0.0034 ND 24.7 ND S407 AKT
NEXN K.AEIKEMLAS*DDEEDVSSKVEK.A 0.0007 0.0024 13.7 21.5 S80 CK II
C11orf58 R.S*ASPDDDLGSSNWEAADLGNEER.K 0.0012 0.0036 21.4 14.6 S15 None
BYSL R.MPQDGS*DDEDEEWPTLEK.A 0.0108 0.2031 21.1 22.6 S98 CK II
MAP1B R.DVMS*DETNNEETESPSQEFVNITK.Y 0.0450 0.0140 6.8 20.2 S1144 CK II
PXN K.TGSSS*PPGGPPKPGSQLDSMLGSLQSDLNK.L 0.0016 0.0144 14.4 14.8 S288 Erk1
GFPT1 R.VDS*TTCLFPVEEK.A 0.0239 0.0064 14.2 3.5 S243 AMPK
AHSG K.CDSSPDS*AEDVRK.V 0.0428 0.0115 12.0 4.1 S138 DNA PK
PLEC1 R.TS*SEDNLYLAVLR.A 0.0092 0.0001 12.0 10.4 S20 PKA
CDC42EP1 K.NAIS*LPQLNQAAYDSLVVGK.L 0.0006 0.0019 8.4 11.3 S121 None
ATP2B1 R.IEDS*EPHIPLIDDTDAEDDAPTK.R <.0000 <.0000 8.6 10.8 S1193 CK II
CFL1 K.LGGS*AVISLEGKPL.- 0.0006 0.0072 10.8 10.3 S155 None
LEO1 K.KYVIS*DEEEEDDD.- 0.0211 0.0024 6.2 9.6 S658 CK II
TBC1D4 R.SLTSS*LENIFSR.G 0.0026 0.0016 9.0 7.3 S570 PKC
SR-A1 R.FDIYDPFHPTDEAYS*PPPAPEQK.Y 0.0015 0.0027 6.3 8.8 S239 Erk1
ZC3H13 R.NTEESS*SPVRK.E 0.0379 0.2075 8.8 7.2 S111 None
MAP4 K.TEVALAKDMES*PTKLDVTLAK.D 0.0004 0.0012 8.6 6.0 S280 Cdk5
SEPT2 K.IYHLPDAES*DEDEDFKEQTR.L 0.0032 <.0000 7.9 8.5 S218 CK II
ARHGEF6 K.S*TAALEEDAQILK.V 0.0199 0.0177 6.3 8.3 S649 PKC
ATP2B1 R.IEDS*EPHIPLIDDTDAEDDAPTKR.N 0.0043 0.0151 8.2 6.6 S1193 None
MATR3 R.RDS*FDDRGPSLNPVLDYDHGSR.S 0.0001 0.0013 6.1 8.2 S188 CLK2
HDAC1 R.MLPHAPGVQMQAIPEDAIPEES*GDEDEDDPDKR.I 0.0368 0.0177 5.4 8.2 S393 CK II
PLEC1 R.T*SSEDNLYLAVLR.A 0.0021 <.0000 8.1 7.0 T19 PKA
ITGA4 R.RDS*WSYINSK.S 0.0334 0.0068 7.8 4.4 S1027 PKA
CEP170 R.QGS*FTIEKPSPNIPIELIPHINK.Q 0.0105 0.0014 2.8 7.7 S838 CAMK2G
USP8 R.SYS*SPDITQAIQEEEK.R 0.1368 0.0092 7.8 7.2 S718 AKT
EIF5B K.WDGS*EEDEDNSK.K 0.0245 0.0009 7.7 4.9 S164 CK II
TP53BP1 K.MVIQGPSS*PQGEAMVTDVLEDQKEGR.S 0.0176 0.0436 6.2 7.2 S1114 Erk1
IFI16 K.VSEEQTQPPS*PAGAGMSTAMGR.S 0.0179 0.0252 0.15 0.24 S153 ERK1
WRNIP1 K.RPAAAAAAGSAS*PR.S 0.1212 0.020 0.36 0.096 S151 None

The T-test was used to identify significantly affected phosphopeptides based on relative peak intensities. The complete list can be found in supplementary Table 2.