Table 3. Kinases and regulators affected by radiation.
| Gene | Peptide | T-test: 2 cGy | T-test: 50 cGy | Change2 cGy | Change 50 cGy |
| ABL1 | K.GQGESDPLDHEPAVS*PLLPR.K | 0.0113 | 0.0008 | 2.6 | 2.9 |
| AKAP11 | R.SVS*PTFLNPSDENLK.T | 0.1771 | 0.0046 | 2.7 | 2.0 |
| MAPK1 | R.VADPDHDHTGFLTEY*VATR.W | 0.0009 | 0.0031 | 2.8 | 2.5 |
| PDPK1 | R.ANS*FVGTAQYVSPELLTEK.S | 0.0043 | 0.0132 | 3.5 | 3.2 |
| PRKAB2 | R.DLSSS*PPGPYGQEMYAFR.S | 0.0009 | 0.0106 | 3.6 | 2.7 |
| G-Test: 2 cGy | G-Test: 50 cGy | Spectra: 0:2 cGy | Spectra: 0:50 cGy | ||
| PRKAR2A | VADAKGDS*ES*EEDEDLEVPVPSR | 16.76 | 11.45 | 38∶11 | 38∶11 |
| AKAP12 | VLSKPPEGVVSEVEMLSS*QER | 0.52 | 7.35 | 0∶1 | 0∶7 |
| AKAP2 | TNGHS*PSQPR | 6.73 | 4.94 | 11∶ 2 | 11∶ 2 |
| MAP3K11 | NVFEVGPGDS*PTFPR | 5.13 | 0.23 | 5∶0 | 5∶3 |
| MAP4K4 | RDS*PLQGSGQQNSQAGQR | 0.78 | 4.37 | 8∶5 | 8∶1 |
| PRKCDBP | APEPLGPADQSELGPEQLEAEVGES*S*DEEPVESR | 0 | 37.86 | 0∶0 | 0∶35 |
| PRKD1 | RLS*NVSLTGVSTIR | 1.28 | 4.13 | 5∶2 | 5∶0 |
| EGFR | ELVEPLT*PSGEAPNQALLR | 5.13 | 4.13 | 5∶0 | 5∶0 |
Shown is a partial list of the kinases and regulatory proteins affected by 2 and 50 cGY of radiation. The top group of peptides were identified using the peak intensity methods and T-test for quantification. The fold change for each peptide relative to control is shown. The bottom group of peptides were identified based on spectral counts using the G-test to assess significance. In both cases, those peptides showing significant change from control values are shown in bold.