Table 15.
(11) The estimated Number of Loci (n) in for Genotypes including or not including HLA DRB1*1501.
| Estimated Number of Susceptibility Genes Required (n) for all Loci | |||||||
|---|---|---|---|---|---|---|---|
| 11 | 12 | 13 | 14 | 15 | 16 | 17 | |
| Frequency of Susceptibility (r) | Estimated (n) the for Genotypes including HLA DRB1*1501 | ||||||
| r = 0.25 | 3 | 3 | 3 | 3 | 3 | 3 | 3 |
| r = 0.33 | 3 - 10 | 3 - 11 | 11 - 11 | 3 - 13 | 11 - 14 | 14 - 15 | 15 |
| r = 0.5 | 10 - 11 | 11 - 12 | 12 - 13 | 13 - 14 | 14 - 15 | 15 - 16 | 17 |
| r = 1 | 11 | 12 | 13 | 14 | 15 | 16 | 17 |
| r = 2 | 11 | 12 | 13 | 14 | 15 | 16 | 17 |
| r = 4 | 11 | 12 | 13 | 14 | 15 | 16 | 17 |
| r = 8 | 11 | 12 | 13 | 14 | 15 | 16 | 17 |
| r = 16 | 11 | 12 | 13 | 14 | 15 | 16 | 17 |
| Frequency of Susceptibility (r) | Estimated (n) the for Genotypes not including HLA DRB1*1501 | ||||||
| r = 0.25 | 12 | 13 | 14 - 15 | 15 - 16 | 16 - 17 | 18 | 19 |
| r = 0.33 | 11 - 12 | 12 - 13 | 14 | 15 | 15 - 16 | 16 - 17 | 18 |
| r = 0.5 | 11 | 12 | 13 | 14 | 15 | 16 | 17 |
| r = 1 | 11 | 12 | 13 | 14 | 15 | 16 | 17 |
| 14 - 15r = 2 | 11 | 12 | 13 | 14 | 15 | 16 | 17 |
| r = 4 | 11 | 12 | 13 | 14 | 15 | 16 | 17 |
| r = 8 | 11 | 12 | 13 | 14 | 15 | 16 | 17 |
| r = 16 | 11 | 12 | 13 | 14 | 15 | 16 | 17 |
(Bold and underlined as designated for "Closeness of Fit" calculations in Table 8)