Table 2.

Phospholipid profile of transfected MLE-12 cells stably expressing mutant SP-C^I73T.

	WT	I73T	P (Anova)
Total phospholipids (nmol/mg protein)	152.80 ± 9.6	153.10 ± 10.0	ns
Phospholipid classes (% of total PL)
Phosphatidylcholine	57.80 ± 1.0	53.70 ± 0.8	< 0.001
Lyso-Phosphatidylcholine	0.60 ± 0.1	1.00 ± 0.8	< 0.001
Phosphatidylglycerol	0.30 ± 0.0	0.20 ± 0.1	ns
Sphingomyelin	6.20 ± 0.3	5.50 ± 0.2	< 0.05
Ceramide	1.80 ± 0.1	1.80 ± 0.1	ns
Glucosyl-Ceramide	0.10 ± 0.0	0.10 ± 0.0	ns
Phosphatidylethanolamine	11.20 ± 0.5	14.70 ± 0.8	< 0.001
Phosphatidylserine	6.50 ± 0.1	6.60 ± 0.3	ns

Data are means of three independent experiments each performed in duplicate. P-values are given.