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. 2010 Nov 30;5(11):e15080. doi: 10.1371/journal.pone.0015080

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Bonaccorsi et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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PBMC samples were isolated from SLE patients and age matched healthy donors and the levels LAIR-1 and NKp44 expression on pDCs were investigated. A representative experiment is shown in panel A. The horizontal bars within the dot-plot depict negative controls with isotype-matched irrelevant mAbs. Results from different independent experiments are summarized in B. Geo-MFI index was used to compare the levels of LAIR-1 and NKp44 expression on pDCs and calculated as: Geo-MFI of positive cells/Geo-MFI of isotype staining cells.