Table 7.
Up- and downregulated pathways in metastatic carcinomas when and (GenMAPP analysis)
| Dysregulated pathways in metastatic canine mammary tumors |
Gene number | Dysregulated pathways in metastatic human breast cancer |
|---|---|---|
| up-regulated pathways | Ranking in a meta-analysis[1] | |
| Cell_cycle | 33 | 1 |
| Cell_cycle_G1_to_S_control_reactome | 22 | 2 |
| DNA_replication_reactome | 25 | 3 |
| Tissue_embryonic_stem_cell | 11 | 6 |
| Proteasome degradation | 7 | 7 |
| down-regulated pathways | ||
| Striated_muscle_contraction | 8 | 4 |
| Focal_adhesion | 11 | / |
| IL-6_NetPath_18 | 5 | 6 |
/not present in the metastatic pathways analysis of human breast cancer