Table 8.
Identification of canine genes in the expression profile of metastatic CMT homologous or similar to the 70-gene prognostic signature for human breast cancer
| Human genes of the 70 prognostic gene profile (van't Veer et al.) |
Homologous genes expressed in metastatic canine tumors | Gene family members expressed in canine tumors |
|---|---|---|
| Homologous genes present on canine gene array | ||
| AP2B1 | AP2B1 | - |
| CCNE2 | - | CCNE1 |
| CDC42BPA | - | - |
| CENPA | CENPA | - |
| COL4A2 | COL2, 16 | |
| DCK | DCK | - |
| DIAPH3 | DIAPH3 | - |
| ECT2 | ECT2 | - |
| EGLN1 | - | - |
| ESM1 | ESM1 | - |
| EXT1 | - | - |
| FGF18 | - | - |
| FLT1 | - | - |
| GMPS | - | GMPS |
| GNAZ | - | - |
| HRASLS | - | - |
| IGFBP5 | - | - |
| LPCAT1 | LPCAT1 | - |
| MCM6 | MCM6 | - |
| MELK | MELK | - |
| MMP9 | - | MMP11 |
| MS4A7 | - | - |
| NDC80 | NDC80 | - |
| ORC6L | ORC6L | - |
| OXCT | - | - |
| PECI | - | - |
| PRC1 | PRC1 | |
| RAB6B | - | RAB10, 7L1, EPK |
| RFC4 | - | RFC2, 3 |
| SCUBE2 | - | - |
| SLC2A3 | - | - |
| STK32 | - | STK3, 4, 11 |
| TGFB3 | - | - |
| UCHL5 | - | UCHL3 |
| ALDH4 | - | ALDH16 |
| FAM2A | - | FAM13B |
| NMU | - | NMB |