Table 4.
Odds ratios of AD for DBH -1021TT+TC vs CC in certain subsets
| Subset | Adjusted* odds ratios of AD (95% CI, p) | ||
|---|---|---|---|
| All | North Europe | North Spain | |
| All | 1.2 (1.06-1.4, 0.005) | 1.2 (1.05-1.4, 0.01) | 1.3 (0.97-1.7, 0.08) |
| Men | 1.6 (1.2-2.0, 0.0002) | 1.7 (1.3-2.2, 0.0002) | 1.5 (0.9-2.55, 0.12) |
| All < 75 years | 1.6 (1.2-2.2, 0.001) | 1.55 (1.1-2.2, 0.02) | 1.8 (1.04-3.0, 0.03) |
| Men < 75 years | 2.2 (1.4-3.3, 0.0004) | 2.2 (1.3-3.8, 0.002) | 1.9 (0.8-4.4, 0.12) |
AD = Alzheimer's disease, DBH = dopamine β-hydroxylase, CI = confidence interval.
* All analyses controlled for centre, age, sex and genotype of apolipoprotein E ε4.
Results in bold are significant at p < 0.05.