Table 2.
Hormonal and metabolic features of adolescents with and without PCOS
| PCOS | |||
|---|---|---|---|
| Control | Rotterdam criteria | NIH criteria | |
| FSH(IU/L) | 5.3(4.4-6.6) | 5.6(4.5-6.9) | 5.6(4.5-6.9) |
| LH(IU/L) | 5.1(3.6-7.5) | 11.0(5.9-16.1) ** | 10.3(6.3-16.2) ** |
| TT(nmol/L) | 1.7(1.5-2.4) | 2.5(2.0-3.2) ** | 2.8(2.3-3.3) ** |
| FT(pg/ml) | 2.9(2.1-3.5) | 4.6(2.6-7.3) ** | 5.1(2.9-8.1) ** |
| Fasting glucose(mmol/L) | 4.7(4.5-4.8) | 4.8(4.5-5.0) | 4.8(4.5-5.1) |
| 2-h glucose(mmol/L) | 5.6(5.0-6.3) | 6.3(5.1-7.1) * | 6.3(5.3-7.1) ** |
| Fasting insulin(μU/ml) | 5.7(4.4-8.3) | 8.8(5.7-13.2) ** | 9.0(5.9-13.2) ** |
| 2-h insulin(μU/ml) | 48.1(35.5-82.4) | 72.7(46.6-131.9) * | 76.7(51.0-139.) ** |
| HOMA-IR | 1.2(0.9-1.8) | 1.9(1.2-2.9) ** | 1.9(1.4-2.9) ** |
| CHOL(mmol/L) | 4.2(3.7-4.7) | 4.5(4.1-5.1) | 4.5(4.1-5.1) |
| TG(mmol/L) | 0.9(0.7-1.2) | 1.0(0.8-1.3) | 1.0(0.7-1.3) |
| HDL(mmol/L) | 1.6(1.4-1.7) | 1.6(1.4-1.9) | 1.5(1.3-1.9) |
| LDL(mmol/L) | 2.6(2.1-2.9) | 2.5(2.1-3.1) | 2.5(2.1-3.2) |
Variables were expressed as median with (interquartile range).
FSH: follicle stimulating hormone; LH: luteinizing hormone; TT: total testosterone; FT: free testosterone; HOMA-IR: Homeostasis Model Assessment of Insulin Resistance; CHOL: total cholesterol; TG: triglyceride; HDL: high-density lipoprotein cholesterol; LDL: low-density lipoprotein cholesterol.
*P < 0.05, **P < 0.01 vs. control.