Table 2. Association of chromosome 9p21 SNPs with carotid intima-media thickness (IMT) (n = 1074).
IMT, Mean±SD (mm) | p* value | |||
rs1333040 | CC (n = 99) | CT (n = 436) | TT (n = 516) | |
CCA IMT | 0.60±0.11 | 0.60±0.13 | 0.62±0.15 | 0.021 |
Bif IMT | 0.63±0.11 | 0.64±0.12 | 0.65±0.14 | 0.125 |
ICA IMT | 0.50±0.08 | 0.49±0.09 | 0.51±0.11 | 0.033 |
*Permutation p value after being adjusted for age, sex, hypertension, diabetes, hypercholesterolemia, body mass index and current smoking.
CCA: common carotid artery.
Bif: bifurcation.
ICA: internal carotid artery.