Table 2.

Prediction of the effects of the c.1958G > C mutation on splicing

Allele	Splice prediction1	ESE score for SC352
Wild type (G)	0.91	4.595
Mutant type (C)	< 0.01	-3

¹Predicted by the Berkeley Drosophila Genome Project (BDGP) splice prediction program.

²Exonic splicing enhancer (ESE) score as predicted by ESEfinder. Its threshold score for SC35 protein is 2.383.

³Below the threshold score.