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. 2010 Nov 30;5(11):e15116. doi: 10.1371/journal.pone.0015116

Figure 2. Genomic localization of the mutation responsible for early calf mortality among the progeny of Finnish Ayrshire bull -YN51.

Figure 2

A. Genomewide half-sib linkage analysis performed with GridQTL for 15,631 autosomal loci for which YN51 was heterozygous. Plot resolution is 1 cM (assumed equivalent to 1 Mb) and phenotypes of 1 were assigned to each of the 5 affected calves and 0 to each of the 13 unaffected calves. The analysis localizes the casual mutation to BTA18 at genome-wide significance level of P = 0.0618. B. Linkage analysis and allele frequency association analysis performed for individual BTA18 SNPs localizes the mutation to the distal end of the chromosome.