Table 3. The smallest recurrent aUPD regions in TN tumor samples.
Chromosomal Band | Start-End Positions | Length (bp) | Possible Candidate Genes | Possible Candidate miRNA |
3p26.2-p26.1 | 3,500,000–4,500,000 | 1,000,001 | SUMF1 | |
3p26.1 | 5,750,000–7,500,000 | 1,750,001 | GRM7 | |
3p22.2# | 37,479,869–38,325,230 | 845,362 | ITGA9, DLEC1 | miR-26a-1 |
3p22.1 | 42,071,245–43,557,137 | 1,485,893 | TRAK1, CCK, LYZL4, VIPR1, SEC22C, SS18L2, NKTR, ZBTB47, KBTBD5, HHATL, CCDC13, HIGD1A, CCBP2, CYP8B1, ZNF662, C3ORF39, SNRK, ANO10 | |
3p21.31 | 49,926,113–51,159,065 | 1,232,953 | TUSC4, SEMA3F, SEMA3B, RASSF1, MAPKAPK3, HYAL1, HYAL2, FUS1 | miR-566 |
3p14.2* | 59,585,338–60,009,495 | 424,158 | FHIT | |
9p23-p22.3* | 13,531,695–14,417,560 | 885,866 | NFIB | |
9p21.3* | 21,948,524–23,513,491 | 1,564,968 | MTAP, CDKN2A, CDKN2B, DMRTA1 | |
9p21.3-p21.2* | 21,014,103–25,983,972 | 4,969,870 | CDKN2A, CDKN2B, TUSC1 | miR-31 |
10q26.12-q26.13# | 122,580,540–123,648,119 | 1,067,580 | FGFR2, K-sam | |
11q22.3 | 103,938,480–105,262,960 | 1,324,481 | CASP1, CASP4, CASP5,CASP12, CARD16, COP1, GRIA4 | |
17q21.31-q21.32# | 41,546,868–42,234,514 | 687,647 | WNT3 | |
17q22# | 53,292,386–53,489,452 | 197,067 | VEZF1, SFRS1 |
*Homozygous deletion,
Amplification.