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. 2010 Nov 30;4(11):e904. doi: 10.1371/journal.pntd.0000904

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t'Kindt et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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The heatmaps show a graphical overview of the fatty acyl (FA) structural properties in diacyl ester phosphatidylcholines (left panel) and diacyl ester phosphatidylethanolamines (right panel). The x-axis shows the total number of unsaturated bonds present in the 2 fatty acyl chains, while the y-axis shows the length of the fatty acyl chains in total number of carbon units. The heatmap intensity of a particular lipid species corresponds to the ratio of the detected average abundance in drug-resistant versus drug-sensitive clones of that lipid. Hence, lipids indicated in red are more abundant in drug-sensitive clones, while lipids in green are more abundant in drug-resistant clones.