Fig. 1.

Schematic diagram of the TRUST-PCASL sequence. The sequence consists of interleaved acquisitions of label and control scans. For each scan, after a train of RF pulses which provide the pseudo-continuous flow driven inversion, a series of non-slice-selective T2-preparation pulses are inserted before the slice-selective excitation pulse to modulate the T2-weighting, the duration of which is denoted by eTE. The subtraction of the control and labeled images yields the ASL signal.