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. Author manuscript; available in PMC: 2011 Dec 1.
Published in final edited form as: Eur J Neurosci. 2010 Oct 19;32(11):1825–1835. doi: 10.1111/j.1460-9568.2010.07463.x

Figure 7. RyRs contribute to depolarization-dependent calcium signal in type III taste cells.

Figure 7

A, Representative trace showing that 20μM ryanodine inhibits the calcium signal that is initiated by opening VGCC in a type III taste cell. B, Pooled results showing inhibition of the calcium signal due to opening VGCCs by 20μM ryanodine in type III cells (n=6, ***P= 0.0005). C, In type III taste cells that were sensitive to ryanodine, the evoked response was reduced an average of 50% by ryanodine (Inhibited). Compared to taste cells that were not sensitive to ryanodine (Not inhibited), this was a significantly larger inhibition (Student’s t-test, n=20, ***P=0.0001).