Fig. 5.

Androgens trigger cytoskeleton changes in MEFs. Quiescent MEFs on coverslips were left unstimulated or stimulated with 10 nM R1881 for 20 min. F-actin was visualized using Texas Red-phalloidin as reported (Castoria et al. 2003). Images show that androgens induce a modification in cell shape and the formation of fan-like protrusions and lamellipodia. They are representative of three independent experiments. Bar, 5 μm.