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. 2010 Nov 11;62(6):585–594. doi: 10.1007/s10616-010-9312-y

Table 1.

Specific growth rate (μ) and specific glucose consumption rate (QGlc) in CCO cultures treated with different concentrations of ammonium-chloride or sodium lactate. Specific lactate production rate (QLac) was determined for lactate treated cells only

Ammonium/Lactate concentration (mM) Ammonium treated cells Lactate treated cells
μ (h−1) QGlc (10−11 mmol h−1 cell−1) μ (h−1) QGlc (10−11 mmol h−1 cell−1) QLac (10−11 mmol h−1 cell−1)
Control 0.0260 6.6 0.0235 7.2 8.3
1 mM 0.0212 6.2 0.0218 6.9 9.2
2.5 mM 0.0143 5.9 0.0201 7.2 8.8
5 mM 0.0116 1.6 0.0186 7.8 9.7* −13.8**
7.5 mM 0.00464 0.7 0.0139 7.3 −11.5
10 mM 0.0042 0.4 0.0112 7.8 −35.4
20 mM 0.0074 6.3 −85.7

*Value for the first 2 days of culture; **Value beyond day 3 of culture

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