Table 1.

Structural imaging studies in ultra-high-risk subjects

^*indicates longitudinal MRI study; ^†indicates psychosis conversion rate during clinical follow-up; ^‡indicates sample size involved in MR follow-up.

UHR, ultra-high-risk subjects; FEP, first-episodic patients; HC, healthy controls; SZ, schizophrenia patients; UHR-P, those who convert to psychosis; UHR-NP, those who did not convert to psychosis; UHR+, UHR subjects with family history of psychosis; UHR-, UHR subjects without family history of psychosis; EPS, UHR subjects in early prodromal states; LPS, UHR subjects in late prodromal states; GHR, genetic-high-risk subjects; DC, depressive controls; L, left; R, right; PANSS, the Positive and Negative Syndrome Scale; VBM, voxel based morphometry; x-BAMM, Brain Activation and Morphological Mapping software; SPM, Statistical Parametric Mapping soft ware; SVM, support vector machine; ACC, anterior cingulate cortex; AI, adhesion interthalamica; CSP, cavum septum pellucidum; CS, cingualte sulcus; OFC, orbitofrontal cortex; PCS, paracingulate sulcus; PCC, posterior cingulate cortex; MTG, middle temporal gyrus; STG, superior temporal gyrus.