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. Author manuscript; available in PMC: 2011 Dec 1.
Published in final edited form as: Peptides. 2010 Sep 8;31(12):2185–2192. doi: 10.1016/j.peptides.2010.08.018

Figure 6. Regulation of gastrin by rapamycin.

Figure 6

(A) Western blot from mice that received ip injection of DMSO or rapamycin (Rapa 1 mg/kg). Phospho-S6 (pS6), eIF-4E, gastrin and β-actin in gastric mucosa were detected using specific antibodies. β-actin and eIF-4E were used as loading controls. Quantification of image analysis of gastric pS6 and gastrin is expressed as mean ±SEM. (B) Results of quantitative PCR analysis of gastrin is expressed as fold change from control using glyceraldehyde 3-phosphate dehydrogenase (GAPDH) as loading control. (C) Plasma gastrin was expressed as mean ±SEM. Six animals were examined for each condition. *, P <0.05 vs. mice receiving DMSO.