Fig. 3.

Lymphatic metastases. a Lymph node metastases from a xenograft tongue tumor of the skin SCC cell line UT-SCC-12A immunohistochemically stained with cytokeratin. Cytokeratin staining is shown in brown and nuclei are stained blue. Original magnification, 100×. b Tongue lymphatic vessels immunohistochemically stained with Lyve-1 containing UT-SCC-12A tumor cells (labeled t). Lyve-1 staining is shown in brown and cell nuclei are stained blue. Original magnification, 400×