Table 5. Disease modifying agent (DMA) treatment practices among physicians who treated at least one patient with optic neuritis per year and completed the corresponding survey questions*.
| Ophthalmologists n=106 | Neurologists n=101 | P value** | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Likelihood of using a DMA | All | Most | Some | None | All | Most | Some | None | |
| With a normal MRI | 1% | 4% | 12% | 83% | 0% | 3% | 6% | 91% | P=0.05 |
| With an abnormal MRI | 14% | 26% | 42% | 18% | 11% | 33% | 41% | 15% | P<0.01 |
| Choice of disease modifying agent | |||||||||
| Ophthalmologists n=11 | Neurologists n=69 | ||||||||
| Interferon beta 1-a (Avonex) | 0% | 17% | 41% | 42% | 7% | 18% | 56% | 19% | p<0.01 |
| Interferon beta 1-a (Rebif) | 0% | 9% | 54% | 37% | 0% | 12% | 67% | 21% | p<0.01 |
| Interferon beta 1-b (Betaseron) | 0% | 9% | 54% | 37% | 1% | 11% | 64% | 24% | p<0.01 |
| Glatiramir acetate (Copaxone) | 0% | 0% | 50% | 50% | 0% | 6% | 66% | 28% | p<0.01 |
Not all surveyed physicians completed all questions. This is why the denominator number of ophthalmologists and neurologists varies from question to question
p values refer to the significance of the difference between the numerical value of the responses of ophthalmologists and neurologists.