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Effect of lisinopril and 20-HEDE on blood pressure in rats transduced with lenti-VECAD-GFP (Group A and B) or lenti-VECAD-CYP4A2 (Group C and D). Lisinopril was given in the drinking water at day 10 post-lentivirus injection (A) or 3 days prior to and the first 10 days after lentivirus injection (B). Group B was treated with lisinopril for the entire duration. Group D was given 20-HEDE daily starting at day 24 (n=4; *p<0.05 vs corresponding group A or B).
