Table I.
Patient No. | Histological Subtype | Age (years) | Sex | Donor | Prior Tx (n) | Failed Prior ASCT | Disease Status Prior to Tx | Time from Dx to Tx (months) |
---|---|---|---|---|---|---|---|---|
1 | AITL | 51 | F | MR | 5 | Yes | SD | 22 |
2 | PTCL-NOS | 61 | M | MUR | 4 | Yes | CR | 29 |
3 | PTCL-NOS | 55 | M | MUR | 3 | Yes | CR | 27 |
4 | T-PLL | 59 | M | MUR | 3 | No | PD | 25 |
5 | AITL | 51 | M | MUR | 6 | Yes | CR | 25 |
6 | PTCL-NOS | 61 | F | MR | 8 | Yes | PR | 144 |
7 | PTCL-NOS | 25 | M | MUR | 1 | No† | CR | 8 |
8 | CTCL-SS | 61 | M | MUR | 7 | No | PD | 20 |
9 | AITL | 72 | M | MR | 3 | No | PR | 6 |
10 | PTCL-NOS | 57 | F | MUR | 4 | No | PR | 21 |
11 | PTCL-NOS | 58 | M | MR | 3 | No | SD | 22 |
12* | NKC-L/L | 63 | M | MR | 1 | No | CR | 9 |
13 | T-PLL | 62 | F | MR | 2 | No | PR | 9 |
14 | T-PLL | 59 | M | MUR | 3 | No | PR | 50 |
15* | AITL | 57 | F | MUR | 1 | No | CR | 6 |
16 | ALCL | 45 | M | MR | 4 | Yes | CR | 48 |
17* | PTCL-NOS | 73 | M | MUR | 2 | No | CR | 6 |
Abbreviations: AITL=angioimmunoblastic T-cell lymphoma; ALCL=anaplastic large cell lymphoma; ASCT=autologous stem cell transplantation; CR=complete remission; MR=matched related; MRD=minimal residual disease; MUR=matched unrelated; NK-L/L=NK-cell leukaemia/lymphoma; PD=progressive disease; PR=partial remission; PTCL-NOS=peripheral T-cell lymphoma, not otherwise specified; CTCL-SS = Cutaneous T-cell Lymphoma-Sezary Syndrome; SD=stable disease; T-PLL=T-cell prolymphocytic leukaemia; Dx=diagnosis; Tx=therapy.
Received NMA HCT as part of the primary therapy due to poor-risk disease characteristics or histology.
ASCT was performed as part of planned tandem autologous-NMA allogeneic transplantation.