. Author manuscript; available in PMC: 2011 May 1.

Published in final edited form as: Ther Deliv. 2010 Jul;1(1):109–131. doi: 10.4155/tde.10.16

Table 4.

Ongoing clinical trials involving microporation techniques for transdermal delivery.

Microporation technique	Sponsor (Collaborator)	Intervention	Disease state/other comments
Electroporation	Karolinska University Hospital (Karolinska Institutet, Swedish Institute for Infectious Disease and Control Cyto Pulse Sciences, Inc.)	DNA vaccine delivered by intradermal electroporation (device: Derma Vax^™)	Colorectal cancer
Electroporation	Uppsala University (Karolinska Institutet and Cyto Pulse Sciences, Inc.)	DNA vaccine delivered by intradermal electroporation (device: Derma Vax)	Prostate cancer
Microneedles	Emory University	Microneedles versus subcutaneous catheter for insulin delivery	Type 1 diabetes
	The University of Hong Kong (Hospital Authority, Hong Kong)	MicronJet versus intramuscular injection of H1N1 vaccine	Vaccination and influenza
	NanoPass Technologies Ltd	Conventional subcutaneous injection versus MicronJet for insulin delivery	Intradermal injections and healthy volunteers
	Hadassah Medical Organization	Intradermal unadjuvanted Pandemrix^® via a microneedle device, compared with intramuscular adjuvanted Pandemrix	Healthy subjects
	NanoPass Technologies Ltd	Delivery of influenza vaccine with microneedles versus intramuscular injection	Influenza vaccine
	Becton, Dickinson and Company	Extended microneedle delivery of insulin	Types 1 and 2 diabetes mellitus
Radiofrequency ablation	Eli Lilly and Company (TransPharma Medical)	Transdermal versus subcutaneous teriparatide (device: ViaDerm^™ drug delivery system)	Osteoporosis

Data taken from [206].