. Author manuscript; available in PMC: 2010 Dec 1.

Published in final edited form as: Diabetes. 2007 Feb 7;56(5):1376–1381. doi: 10.2337/db06-0783

TABLE 2.

Plasma and muscle metabolite data during the 120-min [2-¹³C]acetate infusion

	Insulin-sensitive control	Insulin-resistant offspring
Plasma [acetate] (mmol/l)	0.93 ± 0.12	0.93 ± 0.05
Plasma [2-¹³C]acetate APE (%)	80.8 ± 2.45	87.42 ± 0.80^*
Muscle C₂-glutamate APE (%)	1.20 ± 0.39	1.04 ± 0.20
Muscle C₄-glutamate APE (%)^†	2.52 ± 0.83	2.13 ± 0.43
V_TCA (nmol · g⁻¹ · min⁻¹)	96.1 ± 16.3	59.8 ± 5.1^‡
V_ac/V_TCA (%)	3.4 ± 1.1	2.9 ± 0.6

Data are means ± SE. APE, atom percent excess.

P < 0.01;

^†

calculated from C₂-glutamate assuming 5% anaplerosis;

^‡

P < 0.05.