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. 2010 Sep 7;95(12):2056–2062. doi: 10.3324/haematol.2010.025767

Figure 2.

Figure 2.

Expression of VpreB3 in B-cell tumors. Representative staining for VpreB3 (brown) in (A) endemic BL, (B) sporadic BL, and (C) DLBCL with c-MYC translocation. (D) Chromogenic in situ hybridization staining for c-MYC (blue dots) and chromosome 8 (red dots) in a case of DLBCL showing extra copies of c-MYC (>2 dots per cell) in a subset of cells, and (E) staining for VpreB3 in the same case. (F) Positive staining for VpreB3 in a case of B lymphoblastic leukemia. BL: Burkitt lymphoma, DLBCL: diffuse large B-cell lymphoma.