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. 2010 Sep-Oct;17(5):575–583. doi: 10.1136/jamia.2009.001719

Table 6.

Medications associated with errors in complex tasks

Prescribing error type Examples of errors in complex tasks Medication type Potential implications
Dosage Methotrexate 10 mg instead of 7.5 mg PO weekly Cytotoxic and immunosuppressant Dosage is highly controlled due to toxicity
ciprofloxacin 250 mg tablet instead of IV 200 mg Antibiotic Wrong dose and route; efficacy threatened
Route ciprofloxacin 250 mg tablet instead of IV 200 mg Antibiotic Wrong dose and route; efficacy threatened
Administration time Fosamax PO 70 mg once/week 0800 instead of 0600 Bisphosphonate Administered early to avoid interference of food and other medications with absorption
Frequency Fosamax 70 mg not specified as once weekly Bisphosphonate Potential for overdose
Ural q5*, q4, q3 h instead of q8 h Urinary alkaliniser Maximum dose is up to 4 times daily PRN
Endone PO 5 mg PRN max 10 mg/day prescribed as q1 min PRN up to 2 doses per day Opioid analgesic Not rational
Cessation error trimethoprim not ceased Antibiotic Drug duplication, potential interaction when ciprofloxacin is prescribed
ranitidine not ceased Histamine H2-receptor antagonist Drug duplication when omeprazole is prescribed; irrational therapy
Medical omission ciprofloxacin not added Antibiotic Likely serious consequences
Ural not added Uurinary alkaliniser Comfort; significant
Endone not added Opioid analgesic Inadequate pain relief
omeprazole not added Proton pump inhibitor Symptoms not relieved and potentially dangerous—risk of bleeding.
Date Fosamax PO 70 mg once/week 0600 starting today rather than 1 week from today Bisphosphonate Possible adverse drug reactions
PRN max dose omission Max dose for Ural not specified Urinary alkaliniser Maximum dose is up to 4 times daily
*

Every 5 hours.