Table 6.
Medications associated with errors in complex tasks
Prescribing error type | Examples of errors in complex tasks | Medication type | Potential implications |
Dosage | Methotrexate 10 mg instead of 7.5 mg PO weekly | Cytotoxic and immunosuppressant | Dosage is highly controlled due to toxicity |
ciprofloxacin 250 mg tablet instead of IV 200 mg | Antibiotic | Wrong dose and route; efficacy threatened | |
Route | ciprofloxacin 250 mg tablet instead of IV 200 mg | Antibiotic | Wrong dose and route; efficacy threatened |
Administration time | Fosamax PO 70 mg once/week 0800 instead of 0600 | Bisphosphonate | Administered early to avoid interference of food and other medications with absorption |
Frequency | Fosamax 70 mg not specified as once weekly | Bisphosphonate | Potential for overdose |
Ural q5*, q4, q3 h instead of q8 h | Urinary alkaliniser | Maximum dose is up to 4 times daily PRN | |
Endone PO 5 mg PRN max 10 mg/day prescribed as q1 min PRN up to 2 doses per day | Opioid analgesic | Not rational | |
Cessation error | trimethoprim not ceased | Antibiotic | Drug duplication, potential interaction when ciprofloxacin is prescribed |
ranitidine not ceased | Histamine H2-receptor antagonist | Drug duplication when omeprazole is prescribed; irrational therapy | |
Medical omission | ciprofloxacin not added | Antibiotic | Likely serious consequences |
Ural not added | Uurinary alkaliniser | Comfort; significant | |
Endone not added | Opioid analgesic | Inadequate pain relief | |
omeprazole not added | Proton pump inhibitor | Symptoms not relieved and potentially dangerous—risk of bleeding. | |
Date | Fosamax PO 70 mg once/week 0600 starting today rather than 1 week from today | Bisphosphonate | Possible adverse drug reactions |
PRN max dose omission | Max dose for Ural not specified | Urinary alkaliniser | Maximum dose is up to 4 times daily |
Every 5 hours.