Table 1.
Summary of melanoma-specific studies eliciting patient-derived health utilities
Author, year | Melanoma population |
Source / Elicitation techniques |
Health Statea | Utilityb |
---|---|---|---|---|
Beusterien,[78] 2009 |
Advanced melanoma |
Standard gamble |
Clinical response states | |
Partial response | 0.88 | |||
Stable disease | 0.80 | |||
Progressive disease | 0.52 | |||
Best supportive care | 0.52 | |||
| ||||
Dixon,[21] 2006 | Stage III | EQ-5D | Treatment with Interferon | 0.76 |
Controls | 0.79 | |||
| ||||
Crott,[73] 2004 | Stage III | Time trade- off |
Treatment with Interferon | 0.52 |
Recurrence | 0.23 | |||
| ||||
Kilbridge,[79] 2001 | Early stage melanoma |
Standard gamble |
Interferon with no side effects | 0.92 |
Interferon with mild-moderate side effects | 0.88 | |||
Interferon with laboratory side effects | 0.86 | |||
Interferon with severe side effects | 0.81 | |||
Interferon, recurrence | 0.62 | |||
Recurrence | 0.61 | |||
Disease free survival | 0.96 | |||
| ||||
Chen,[80] 2004 | Stages I, II, III |
Time trade- off |
Stage I (Actual / Hypothetical) | 0.93 / 0.94 |
Stage II (Actual / Hypothetical) | 0.97 / 0.73 | |||
Stage III (Actual / Hypothetical) | 0.52 / 0.50 | |||
FACT-M validation study |
EQ-5D | Stage I | 0.90 | |
Stage II | 0.87 | |||
Stage III | 0.82 | |||
Stage IV | 0.82 |
Abbreviations: EQ-5D, EuroQol EQ-5D
The health states presented in this table do not reflect the entirety of health states estimated in these studies.
When separate utility coefficients were estimated for multiple time points, the earliest time point was presented.