Table 4.
Frequency of diarrhea (%) | ||||
---|---|---|---|---|
Treatments | Dose (mg/kg) |
Day 1 | Day 7 | Day 14 |
Control | 0 | 0 | 0 | |
EEA | 150 | 0 | 0 | 0 |
EEA | 300 | 0 | 0 | 0 |
EEA | 600 | 0 | 8.3 | 0 |
Senna | 150 | 100 | 100 | 91.7 |
Senna | 300 | 100 | 100 | 100 |
EEA (150, 300, and 600 mg/kg) and senna (150 and 300 mg/kg) were orally administered daily to constipated rats that had been maintained on a low-fiber diet for 5 weeks. EAA or senna were orally administered to the rats, then the frequency of diarrhea was measured over the next 16 h. n = 12.