Table 2.
VBM analysis | Region | Left hemisphere coordinates (mm) |
t-score | z-score | Right hemisphere coordinates (mm) |
t-score | z-score | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
x | y | z | x | y | z | ||||||
T1-weighted grey matter | |||||||||||
Tourette syndrome < controls | VLPFC | −53 | 35 | −6 | 4.8 | 4.5 | 45 | 38 | −12 | 4.9 | 4.5 |
OFC | 0 | 33 | −26 | 5.3 | 4.8 | ||||||
Operculum | −39 | −3 | 7 | 4.4 | 4.1 | 58 | −13 | 16 | 3.9 | 3.7 | |
rACC | 7 | 44 | 1 | 3.7 | 3.6 | ||||||
Tourette syndrome > controls | Putamen | −27 | −10 | 3 | 3.3 | 3.2 | 27 | −3 | 9 | 4.5 | 4.2 |
Interaction Group × Age | rACC | 5 | 45 | 0 | 4.8 | 4.4 | |||||
tourette syndrome < controls | |||||||||||
ADHD + <ADHD− | Hippocampus | −23 | −33 | 0 | 4.6 | 4.3 | 24 | −36 | 0 | 3.6 | 3.5 |
IPC | −60 | −46 | 25 | 4.4 | 4.11 | ||||||
Mean diffusivity grey matter | |||||||||||
Tourette syndrome > controls | OFC | 9 | 29 | −24 | 3.9 | 3.7 | |||||
Fractional anisotropy grey matter | |||||||||||
Tourette syndrome > controls | SI | −17 | −37 | 64 | 3.1 | 2.9 | 27 | −45 | 54 | 5 | 4.5 |
Fractional anisotropy white matter | |||||||||||
Tourette syndrome < controls | CC | 3 | 21 | −3 | 4.5 | 4.1 | |||||
Mean diffusivity white matter | |||||||||||
Tourette syndrome < controls | SI | −21 | −30 | 70 | 3.4 | 3.2 | 10 | −37 | 70 | 3.3 | 3.1 |
Coordinates [x, y, z] refer to the Montreal Neurological Institute (MNI) standard stereotactic space.
rACC = rostral anterior cingulate cortex; CC = corpus callosum; IPC = inferior parietal cortex; OFC = orbitofrontal cortex; SI = primary somatosensory cortex; VLPFC = ventrolateral prefrontal cortex.