Table 4.
Voxel-based cortical thickness analysis | Region | Right hemisphere coordinates (mm) |
t-score | z-score | Right hemisphere coordinates (mm) |
t-score | z-score | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
x | y | z | x | y | z | ||||||
T1-weighted grey matter | |||||||||||
Tourette syndrome > controls | SI | −29 | −48 | 64 | 3.5 | 3.4 | 35 | −45 | 61 | 3.6 | 3.5 |
PMd | 18 | −15 | 62 | 4 | 3.7 | ||||||
Tourette syndrome < controls | OFC | −12 | 35 | −21 | 4.1 | 4 | |||||
VLPFC | −44 | 35 | −11 | 4.6 | 4.3 | 46 | 35 | −15 | 4.4 | 4.1 | |
Operculum | −35 | −7 | 18 | 3.8 | 3.6 | 55 | −12 | 19 | 4.5 | 4.2 | |
Hippocampus | −33 | −30 | −11 | 3.3 | 3.2 | 23 | −30 | −15 | 3.5 | 3.4 | |
Amygdala | −30 | −11 | −18 | 3.1 | 3 | 24 | −7 | −11 | 3.7 | 3.6 | |
ADHD+ < ADHD– | Hippocampus | −29 | −37 | −3 | 4.9 | 4.5 | 24 | −36 | 0 | 4 | 3.7 |
IPC | −59 | −49 | 28 | 4.4 | 4.1 | ||||||
T1-weighted grey matter—regression | |||||||||||
YGTSS | |||||||||||
Tourette syndrome—negative correlation | OFC | −3 | 33 | −20 | 3.1 | 3 | |||||
VLPFC | −41 | 21 | −9 | 3.3 | 3.1 | 51 | 27 | −6 | 3 | 2.9 | |
PUTS | |||||||||||
Tourette syndrome—positive correlation | SI | −48 | −13 | 33 | 4.7 | 4 | |||||
PFC | 19 | 24 | 43 | 4.2 | 3.7 |
Coordinates [x, y, z] refer to the Montreal Neurological Institute (MNI) standard stereotactic space.
IPC = inferior parietal cortex; MI = primary motor cortex; OFC = orbitofrontal cortex; PMd = dorsal premotor cortex; SI = primary somatosensory cortex; VLPFC = ventrolateral prefrontal cortex.