Figure 6.
89-year-old woman underwent a uterine cancer surgery followed by 50-Gy fractionate radiation therapy 40 years previously. (a) In 10 × 10 cm area of radiation, 5 × 10 cm area was exposed. Bone, fascia, and muscle as well as skin and fat were affected. (b, c, d) After careful debridement, 3.8 × 107 cells/5 mL were applied over the wound bed and margins and soaked with artificial dermis. In a few days postoperatively, bFGF was sprayed over the peeled-off inner regenerated tissue for 21 days. (e) In 1.5 years postoperative view. The regenerated tissue remained durable, soft, and pliable.