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Secondary structure prediction of hNEIL1 and its E. coli prototype endonuclease VIII (Nei) by PrDOS (a,c) and PONDR (b,d) softwares. The protein sequences were obtained from NCBI database. Sequences in red in PrDOS and a score of 0.5 and above in the PONDR plot indicate disordered structures. The disordered C-terminal segment (wiggled line) of hNEIL1 is absent in Nei
