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. 2010 Oct-Dec;2(4):350–355. doi: 10.4103/0975-7406.72139

Table 1.

Effect of MEEV on lipid parameters, body weight, and fat pad weight in normal and hypercholesterolemic rats

Parameters Group 1 Group 2 Group 3 Group 4 Group 5
TC (mg/dl) 79.25±0.42 203.80±0.49a*** 162.16±0.45b*** 143.61±0.49b*** 73.30±0.33b***
TG (mg/dl) 58.9±0.74 135.1±0.37a*** 115.6±0.42b*** 109.1±0.51b*** 55.3±0.19b***
HDL-c (mg/dl) 29.32±0.63 15.00±0.41a*** 16.16±0.80bNS 16.82±0.28bNS 17.02±0.21b***
LDL-c (mg/dl) 73.34±0.48 179.78±0.97a*** 142.48±0.48b*** 125.19±0.41b*** 65.64±0.63b***
VLDL-c (mg/dl) 11.78±0.54 27.01±0.65a*** 23.52±0.88b* 21.82±1.02b*** 11.06±1.03b***
Atherogenic index 2.70±0.54 13.58±0.42a*** 10.03±0.64b*** 8.53±0.56b*** 4.30±0.74b***
HMG-CoA/Mevalonate ratio 11.24±0.83 3.31±0.12a*** 5.86±0.34b** 7.32±0.49b*** 7.89±0.37b***
Body weight (g) 249.67±4.12 327.57±5.89a*** 284.24±4.43b*** 269.16±2.72b*** 233.84±3.44b***
Mesenteric fat pad weight (g) 0.28±0.12 0.87±0.29a** 0.40±0.03b* 0.31±0.18b** 0.17±0.08b***

Values are mean ± SEM, n=6 animals in each group. Comparisons were made between: a, group I vs. II and b, group II vs. III, IV, and V. Symbols represent statistical significance:

*

P<0.05,

**

P<0.01,

***

P<0.001