Table 4.
Effect of the quantity of drug concentration in donor cell on skin permeation of LHCl (n = 3)
| Study code | Drug concentration (μg/ml) | + Permeability coefficient Kp × 102 cm/hr1 | Enhancement factor (E.F.) |
|---|---|---|---|
| PS1 (D/W*) | 100 | 6.322 (± 0.013) | 1.00 |
| PS10 (D/W) | 200 | 7.367 (±0.016) | 1.16 |
| PS2 (IPB) | 100 | 4.458 (± 0.015) | 1.00 |
| PS11 (IPB) | 200 | 5.537 (±0.011) | 1.24 |
+
Results are the mean of triplicate observations. SEM values are given in parenthesis
*
Distilled water. PS1 was control for PS 10. PS2 was control for PS 11