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. Author manuscript; available in PMC: 2010 Dec 2.
Published in final edited form as: Cancer Res. 2006 Oct 15;66(20):9878–9885. doi: 10.1158/0008-5472.CAN-05-4157

Figure 5.

Figure 5

Functional E-cadherin is necessary for the detection of TβRII. A, addition of an E-cadherin neutralizing antibody (DECMA) disrupts the interaction between E-cadherin and TβRII in both Ecad and Ecyto cells as shown by coimmunoprecipitation with antibody against FLAG. B, cells cultured without calcium show lower levels of E-cadherin, which is associated with lower TβRII expression levels. C, cells cultured in the presence of neutralizing antibody show a coordinated decrease of E-cadherin and TβRII levels after 3 hours of treatment. Actin serves as a loading control.