Figure 5.

Pioglitazone treatment enhances resolution of neutrophilia and ameliorates inflammation in CGD mice. Mice were treated as described in Figure 4. The time course of neutrophilia was determined (A, with a blowup of the early time points shown in B), and cytokines were measured in lavage supernatants (CGD mice shown) (C). Data represent mean ± SE; N = 8 mice per time point. #P ≤ .02 compared with vehicle-treated CGD mice at the respective time points, and α,*P ≤ .01 compared with WT mice treated with vehicle, at the respective time points.