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. Author manuscript; available in PMC: 2011 Mar 1.
Published in final edited form as: J Immunol. 2010 Feb 5;184(5):2401–2409. doi: 10.4049/jimmunol.0902448

FIGURE 2.

FIGURE 2

Selective loss of CD8+ CL-4 T cells in response to the altered Japan epitope following natural virus infection in vivo. Purified CD8+ Thy1.2+ splenic CL-4 T cells were labeled with CFSE and injected i.v. into Thy1.1+ recipient mice that were infected i.n. with PR/8 or Japan virus 1 d later. At the indicated times postinfection, MLNs, lungs, and the spleen were harvested, and the absolute numbers of donor CL-4 T cells were calculated from organ cell counts and CD8+ Thy1.2+ percentages. Error bars represent SD.