. 2008 Jun;21(2):99–113. doi: 10.1089/vim.2008.0002

Table 1.

Phenotypic Variations that Define Functional Subsets of Memory T Cells

Phenotypic markers	Memory subsets	Functions	References
CCR7	Effector-memory	Effector cytokine production	6,118–120,141
CD62L	CD62L^lo/CCR7⁻ Central-memory CD62L^hi/CCR7⁺	IL-2, high proliferation
CD45RB	CD45RB^hi	Low effector responses	16
	CD45RB^lo	Effector cytokines
VLA1	CD49b⁺	TNF-α, protective	48, 62
VLA-2 (CD49b)	CD49b⁻	IL-10
	VLA-1⁺	Th-1 functions
CD27	Effector memory	Effector cytokine production	18, 46, 53
	CD27^lo Central memory CD27^hi	IL-2, high proliferation
CD28	CD28⁺	All resting memory	98, 106, 150
	CD28⁻	Newly activated memory/CMV downmodulation
CD43	CD43^lo	Effector cytokines	53, 71, 100
	CD43^hi	Naive
CCR6, CCR4	CCR6⁺CCR4⁺	IL-17	2, 9
CXCR3	CXCR3⁺	Th-1 responses	68, 131