Table 2. Ability of simulated interventions to interrupt malaria transmission and control reintroductions.
Intervention | Low transmission (EIR ∼3) | Moderate transmission (EIR ∼15) | ||
% interrupting transmission (timea) | % where introductions become established | % interrupting transmission (timea) | % where introductions become established | |
T90b | 0 | - | 0 | - |
MDAc | 100 (174–1,088) | 100 | 40 (206–414) | 100 |
Bedd | 100 (1,235–4,458) | 0 | 0 | - |
T90+Bed | 100 (1,034–1,904) | 0 | 0 | - |
MDA+Bed | 100 (171–1,209) | 0 | 65 (201–774) | 100 |
MDA+T90 | 100 (174–337) | 0 | 80 (205–679) | 0 |
MDA+Bed+T90 | 100 (71–371) | 0 | 85 (200–562) | 0 |
Range of time (days) until transmission is interrupted. Time to interruption is the first occurance of 150 days with no infectious mosquitoes.
90% chance of symptomatic individuals receiving curative treatment; time between appearance of symptoms and treatment is decreased (compared to baseline).
100% of population is treated with a curative dose at start of intervention and 40 days later with same drug as used for chemotherapy.
80% of the population receive (and use) bed nets; use of a bed net reduces mosquito exposure by 80%.