Table 2.

One-pot synthesis of allylic amines using an organocatalytic aziridination-Wharton sequence

Entry	Enone (1)		Product (7)		Yield (%)*	ee (%)†
1	1a		7a		56	96
2‡	1a		ent-7a		52	95
3	1b		7b		48 (37)§	98 (98)§
4	1d		7d		50 (50)§	97 (97)§
5	1e		7e		57	99
6	1f		7f		61	99
7‡	1f		ent-7f		69	99
8	1g		7g		42	94
9	1h		7h		52	97

^*Yields of isolated products.

^†Determined by chiral stationary phase HPLC.

^‡The quasi-enantiomer of the catalyst was used (2b, see Scheme 5).

^§Results for the sequence performed in two separate steps.