Table 1.

Effect of reaction parameters on the catalytic asymmetric γ-addition of a malonate ester to a γ-substituted allenoate

Entry	Change from the “standard conditions”	Yield, %*	ee, %
1	None	98	95
2	No (S)-1	< 5	—
3	No 2-methoxyphenol	24	71
4	Room temperature instead of −30 °C	91	90
5	(S)-2 instead of (S)-1	80	95
6	(S)-3 instead of (S)-1	< 5	—
7	(S)-4 instead of (S)-1	93	93
8	(+)-TangPhos instead of (S)-1	50	17

All data are the average of two experiments.

^*The yield was determined by GC analysis with n-decane as an internal standard.