Table 2.

Catalytic asymmetric γ-additions of malonate esters to γ-substituted allenoates

Entry	R1	R2	R	Yield, %*	ee, %
1	Me			94	94
2				88	92
3	(CH2)3CI			91	93
4	(CH2)4OTIPS			78	87
5	(CH2)4OBn	Et	Allyl	78	90
6				71	94
7	(CH2)3CO2Me			77	94
8				71	86
9	n-Pr			84	93
10		Bn	Et	65	90
11	CH2OMe			74	93
12†				71	85

All data are the average of two experiments.

^*Yield of purified product. Only the E isomer is observed.

^†15% (S)-1 was used.