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. Author manuscript; available in PMC: 2010 Dec 2.
Published in final edited form as: Immunity. 2010 Feb 18;32(2):227–239. doi: 10.1016/j.immuni.2009.12.006

Figure 4. Unimpaired Endocytosis and Phagocytosis in Atg5−/− DCs.

Figure 4

Purified splenic DCs from WT or Atg5−/− chimeras were incubated with the indicated amounts of OVA-Alexa 488 for 1 hr at 4°C or 37°C (A) or irradiated PKH26-labeled MHC II−/− splenocytes on ice or at 37°C in the presence or absence of 10 μM cytochalasin D for 3 hr (B). Uptake of OVA (A) or PKH26-labeled apoptotic cells (B) by DCs was determined by flow cytometry. The results shown are representative of three independent experiments. Numbers indicate percentages.