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. 2010 Nov;131(3):395–404. doi: 10.1111/j.1365-2567.2010.03313.x

Figure 2.

Figure 2

Increased expression of cytokines and chemokines in Dusp1−/− mice after caecal ligation and puncture (CLP). Mice were killed 12 hr after CLP. (a) Serum levels of interleukin-6 (IL-6), IL-10, CCL3 and CCL4. Mice were backcrossed to C57BL/6. Mean and SEM (n = 5) are shown. (b) Dusp1 expression in spleen and liver after CLP. (c, d) Induction of inflammatory gene expression 12 hr after CLP in the spleens (c) and livers (d) of wild-type (WT) and Dusp1−/− mice (n = 5). Mean and SEM from one experiment out of two with similar results are depicted. Asterisks indicate P < 0.05 in Student's t-test.