Table 5.
Effect of different dose levels of Mahayograj guggulu on the biochemical parameters in albino rats
| Parameter studied | Control (distilled water) | TED (54 mg/kg) | TED × 5 (270 mg/kg) | TED × 10 (540 mg/kg) |
|---|---|---|---|---|
| Blood glucose (mg/dl) | 78.83 ± 3.67 | 66.50 ± 4.66 | 75.83 ± 3.36 | 69.33 ± 3.65 |
| Serum cholesterol (mg/dl) | 58.83 ± 7.09 | 64.33 ± 7.84 | 66.66 ± 3.42 | 63.00 ± 3.07 |
| Serum triglycerides (mg/dl) | 117.50 ± 15.53 | 104.33 ± 16.26 | 124.33 ± 17.95 | 113.50 ± 6.34 |
| Blood urea (mg/dl) | 38.00 ± 3.25 | 34.83 ± 1.62 | 36.83 ± 2.89 | 39.00 ± 2.73 |
| Serum creatinine (mg/dl) | 0.98 ± 0.07 | 0.90 ± 0.03 | 00.86 ± 0.04 | 00.93 ± 0.06 |
| Serum alkaline phosphatase (IU/L) | 137.67 ± 32.66 | 296.00 ± 31.62** | 266.66 ± 25.04** | 251.16 ± 33.36* |
| SGOT (IU/L) | 276.67 ± 20.77 | 356.00 ± 41.84 | 288.66 ± 42.25 | 428.60 ± 88.86 |
| SGPT (IU/L) | 89.00 ± 6.82 | 107.00 ± 27.25 | 084.50 ± 4.67 | 102.20 ± 9.77 |
| Serum total protein (g/dl) | 7.43 ± 0.40 | 7.65 ± 0.26 | 07.10 ± 0.15 | 07.08 ± 0.13 |
| Serum albumin (g/dl) | 3.55 ± 0.32 | 3.53 ± 0.22 | 03.80 ± 0.26 | 04.08 ± 0.10 |
| Serum globulin (g/dl) | 3.80 ± 0.16 | 4.11 ± 0.39 | 03.30 ± 0.28 | 03.00 ± 0.11** |
Data: mean ± SEM,
*
P < 0.05,
**
P < 0.01